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Tadaflo 5 mg works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for the breakdown of cyclic GMP (cGMP). Cyclic GMP helps relax the smooth muscles and increase blood flow in the penis. By blocking PDE5, Tadalafil allows cGMP to remain active longer, leading to better blood flow to the penis during sexual arousal.
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http://www.genericday.com/tadaflo-5-mg.html